California Tech v. 122:3, October 15, 2018

The California Tech VOLUME CXXII NUMBER 3 PASADENA, CALIFORNIA TECH@CALTECH.EDU OCTOBER 15, 2018 Frances Arnold Wins 2018 Nobel Prize in Chemistry WHITNEY CLAVIN Office of Strategic Communications Frances H. Arnold, enterprise that has both deep scientific significance and enormous practical consequences," says David A. Tirrell, Caltech's provost, the Carl and Shirley Larson engineering from Princeton and chemicals. University in 1979 and her graduate degree in chemical engineering from UC Berkeley in 1985. She arrived at Caltech as a of Chemical Engineering, Bioengineering Biochemistry, visiting associate in 1986 H. Corcoran Professor of professor in 1987, associate enzymes," according to the professor in 1996. In 2000, she was named the Dick and Barbara Dickinson Professor A number of additional enzymes produced through directed evolution are now used for a host of products, including biofuels, agricultural chemicals, paper products, and pharmaceuticals. For example, the method led to a better way to produce a drug for treating type 2 diabetes. 2008). She received the 2011 National Medal of Technology and Innovation and Wan inducted into the National Inventors Hall of Fame in 2014 She has won numerous other awards, including the 2017 Sackler Prize in Convergence Research from the NAS and the Society of Women Engineers 2017 Achievement Award. by Arnold in the 1990s, is a bioengineering method for creating new Today, the method is used in hundreds of laboratories and companies that make detergents to biofuels to medicines. Enzymes created technique have replaced toxic chemicals in many industrial processes. with George P. Smith of the Columbia, who developed a "phage display" method for evolving proteins, and Sir Gregory P. Winterofthe MRC United Kingdom, who used phage display for evolving antibodies. One half of the prize, which comes with an award of 9 million Swedish krona (about $1 million), goes to Arnold, with the other half shared by Smith and Winter. Arnold received the call at a hotel in Dallas, Texas, at around 4 a.m. local time; she was scheduled to give a lecture today at UT Southwestern, but had to reschedule to fly back to California. She says she was in a "deep, deep sleep" when awakened by the call. "I am absolutely floored. I have to wrap my head around this. It's not something I was expecting." "Frances's work on directed evolution is beautiful example of an decades of commitment to exploring a powerful idea, Frances has transformed the fields of protein chemistry, catalysis, and biotechnology. She has changed the way we think about things and the way we do things." make proteins and how we catalysts," says Jacqueline K. Barton, Caltech's John Chemistry and the Norman Davidson Leadership Chair of the Division of Chemistry and Chemical Engineering. "Through this work, she has broadened the repertoire of biological chemist, and evolution her design process," Arnold. the best chemist but I do appreciate evolution." Arnold was born on July 25, 1956, in Pittsburgh, Pennsylvania. She received her undergraduate degree in mechanical and aerospace Biochemistry; the Linus Pauling Professor in 2017. She became the Benjamin M. Rosen Bioengineering in the same way that breeders mate cats or dogs to bring out desired traits. To perform the method, scientists begin encodes a particular enzyme (a molecule that catalyzes, reactions). An Frances Arnold - Credit to Caltech enzymes is produced and then tested for a desired trait. The top-performing enzymes are selected and the process is repeated to further More Arnold and her colleagues used directed evolution to persuade bacteria to make chemicals not found in nature, including molecules containing silicon-carbon or boron-carbon bonds, or bicyclobutanes, which contain energy-packed carbon rings. By using bacteria, researchers can potentially make these chemical compounds in "greener" ways that are more economical and produce less toxic waste. "My entire career I have been concerned about the damage we are doing to the planet and each other," said Arnold when she won the 2016 Millennium Technology Prize, granted by the Technology Academy Finland "Science and technology can play major role in mitigating our negative influences on the environment. Changing behavior is even more important. However, I feel that change is easier when there are good, economically viable alternatives to harmful habits." performances. For instance, in 2009, Arnold and her team engineered enzymes that break down cellulose, the main component of plant cell walls, creating better catalysts for turning agricultural wastes into fuels Arnold was the first woman to receive the 2011 Charles Stark Draper Prize from the National Academy of Engineering (NAE). She is among the small number of individuals, and the first woman, elected to all three branches of the National Academies: the NAE (2000), the National Academy of Medicine (2004; it was then called the Institute of Medicine), and the National Academy of Sciences (NAS; She is a member of the American Academy of Arts and Sciences and the American Philosophical Society, and is a fellow of the American Association for the Advancement of Science and the Royal Academy of Engineering. "Frances's methods have been adopted by scientists and engineers around the world, and many more have been inspired by her vision and her impact on chemical science and technology," says Tirrell. "Her extraordinary accomplishments reflect the unconventional research environment at Caltech, where scholars are encouraged to dream, to take risks, and to venture beyond the constraints of disciplinary boundaries." The 2018 Nobel Prize in Chemistry is the 39th Nobel Prize awarded to Caltech faculty and alumni. Other Caltech faculty with Nobel Prizes include: Kip S. Thorne (BS '62) and Barry C. Barish, winners of the 2017 Nobel Prize in Physics with Rainer Weiss; Robert Grubbs, winner of the 2005 Nobel Prize in Chemistry with Yves Chauvin and Richard R. Schrock; David Politzer, recipient of the 2004 Nobel Prize in Physics with David J. Gross and Frank Wilezek; Rudy Marcus, sole winner of the 1992 Nobel Prize in Chemistry; and David Baltimore, winner of the 1975 Nobel Prize in Physiology or Medicine with Renato Dulbecco and Howard M. Temin. IN THIS ISSUE SKYMALL | PAGE 4 SODA 12-PACK, MISFORTUNE COOKIES AND TINY VIOLIN SPORTS | PAGE 5 SHANKER, WEI PLACE FOURTH AT NATIONALS PUZZLES | PAGE 6 BRIDGES, MATHDOKU AND DIAGRAMLESS CROSSWORD HUMOR | PAGE 8 SILENT OBSERVATIONS 2 OCTOBER 15. 2018 ANNOUNCEMENTS THE CALIFORNIA TECH Upcoming Events EDITORS-IN-CHIEF vendors on how you and your family can become better prepared. ASCIT Minutes Meetings are every week in SAC 13 The Upcoming Events column serves to inform students of upcoming events. The list is compiled by the Editors-in-Chief from information available around campus. GSC Voter Registration Fair Monday, October 15th - Wednesday, October 17th | 11:30 AM - 1:30 PM | San Pasqual Walk This one's pretty self-explanatory. Caltech's very OwI Graduate Student Council will be hosting a voter registration fair outside Chandler Cafe where you, yes you, can become a registered voter in the great state of California and vote on all of the ballot measures we are known for. CDC Career Fair Tuesday, October 16th | 10 AM - 2 PM | Braun Gym Learn practical, behavioral strategies for responding differently to old habits; Respond differently to unhelpful thoughts like, "I can just get up early and do this - Since Donut is down, any course concerns should be directed to an ARC rep. If you would like to remain anonymous, the rep you contact will not share your identity. V.P. of Non-Academic Affairs (Sarah): - Rotation happened. This year yielded the best percentage of frosh who got their top Career Fairs are the best opportunity to make connections with recruiters who make hiring decisions. Many firms have summer internships that are a first step to employment in the firm. This is a unique opportunity for you to talk with recruiters face to face and ask questions about their companies and the positions they have available. Come impress the recruiters with your intelligence, experience and inquisitiveness! choice (76%); 100% got top 3 or above. Most houses filled; houses with missing beds reminder system to keep the lessons from the workshop fresh. had members that moved back in from Bechtel. - Trying to make it easier to schedule events, in particular smaller events with alcohol. - The IC will continue to discuss rotation. There will be open meetings every Tuesday at noon in SAC B126. Last Day for Adding Courses and Removing Conditions and Incompletes Friday, October 19th Director of Operations (Varun): - Not in attendance. - Club funding is due November 2. ASCIT BoD will meet that weekend to decide on club funds. ARC Frosh Rep Interviews Saturday, October 20th Treasurer (Dana): - Many last-minute club reimbursements were filed over the summer. The fiscal year has ended for last year's budget; clubs can no longer get reimbursed. Lab Safety 101 Training You too can represent the Class of 2022 - ASCIT BoD will discuss and plan this year's budget in the near future. Social Director (Alice): Wednesday, October 17th | 3 PM | Keith on the Academics and Research Committee. - End of Rotation party happened last Friday (October 5). Spalding B117 Sign up for this lucrative interview by 5pm - Trivia Night happened last night (October 11). Friday, October 19th either on the RF arches - Planning an escape room event next weekend (date TBD). A sign-up form will be sent This course is designed to prepare or online! out early next week. incoming researchers work in - Contacted the Rath about doing happy hour; the event will tentatively be held on Fri- laboratory at the Institute. Topics include SURF Seminar Day day November 2. Drinks will be discounted. laboratory organization; injury prevention; Saturday, October 20th | 9 AM - 5:30 PM - Discuss using Lyft codes for free events such as hikes, festivals, exploring LA, etc. fire, earthquake, chemical and radioactive | Multiple Locations Secretary (Rachel): materials incident management; general - Nothing to report. laboratory safety; chemical storage and the Please join us at this exciting symposium safe handling of chemicals; preparation where over 225 students will present their for experiments; electrical and mechanical research projects and discuss their findings safety; and an overview of services provided in 25 concurrent oral sessions plus a poster by the EH&S Office. session. We invite all members of our community - students, faculty, alumni, staff, James Michelin Distinguished friends, family, and guests - to celebrate our If anyone has any questions or concerns about a section of the minutes please email the appropriate officer. We are happy to answer any questions. Meeting Adjourned: 12:56 PM ARC Minutes Visitors Program - The Science of students' achievements! Shakespeare - Dan Falk Meetings are every week in SAC 13 Wednesday, October 17th | 7 PM | Baxter Lecture Hall Folk Music at Caltech - Bill Staines Saturday, October 20th | 8 PM | Beckman Institute Auditorium Present: Erika Salzman, Arushi Gupta, Michael Yao, Alejandro Lopez, Alice Jin, LC Chen William Shakespearelived at a remarkable time - a period we now recognize as the first phase of the Scientific Revolution - and yet "Shakespeare" and "science" are rarely uttered in the same breath. However, as award-winningjournalist Dan Falkhasfound, a reassessment is at hand. In this illustrated talk, Falk will explore Shakespeare's interest in the scientific discoveries of his time, with a particular focus on the changing conceptions of the cosmos, from Aristotle to Copernicus and Galileo. 2018 ShakeOut and Personal Preparedness Fair Thursday, October 18th | 10:18 AM, 11 AM - 1 PM | Avery Courtyard October 18 1S the Great California ShakeOut earthquake drill. At 10:18am a Caltech Alert will let everyone know it's time to "Drop, Cover, and Hold On!" Once you've practiced your earthquake procedures, come over to Avery Courtyard between 11am - 1pm, for our annual Personal Preparedness Fair. The Fair will include live demonstrations, giveaways, and information from campus resources, local emergency agencies, and Coping with Procrastination and Work Avoidance Friday, October 19th | 4 PM | Sherman Fairchild Library 328 Counseling Services is pleased to offer a workshop on coping with procrastination and work avoidance. It's open to all graduate and undergraduate students - come join us! No signup is necessary - just show up. We'll meet in 326 Sherman Fairchild Library from 4.00 - 6.00. If you can't make it to this session, the workshop will repeat on Friday, November 9th in the same location. Learn toolsforcoping with procrastination While we have enjoyed Bill Staines's songs for decades, whether on recordings or by such people as Peter, Paul, and Mary, Tommy Makem and the Clancy Brothers, Nanci Griffith, Priscilla Herdman, Jerry Jeff Walker, and many others, he has seldom performed here in Southern California in recent years. Songs like "All God's Critters," "The Roseville Fair," "Child of Mine," and "River" have become folk music classics. Composer David Amram once described Bill as "a modern day Stephen Foster. His music will be around a hundred years from now." After a few years of trying, we're glad to announce that Bill will be making his Caltech debut at last! Explore JPL Seminar Monday, October 22th | 12 PM | Noyes This lunch-time program is designed to help undergrads learn more about the research happening at the Jet Propulsion Lab and connect them with possible SURF mentors for next summer. Lunch is included for those who RSVP. ASCIT Board of Directors Meeting Minutes for October 12, 2018. Taken by Rachel Sun. Officers Present: Sakthi Vetrivel, Sarah Crucilla, Alice Zhai, Dana He, Rachel Sun Guests: Call to Order: 12:30 pm President's Report (Sakthi): - Donut has crashed. It will be back up soon. - First ACRL meeting has happened. ACRL will send out a rotation survey, and will discuss issues such as the board plan, rotation, and mandatory housing requirements - Schedule a meeting for ASCIT BoD to plan this year's budget and schedule a retreat date. Officer's Reports: V.P. of Academic Affairs (Erika): - Not present. Report submitted prior to meeting. - Course capture (lecture recording) is underway; anyone interested in recording lectures for pay should contact the ARC. - Unix Shell Software Seminar sign-ups are out; the seminar will take place on October Meeting 1. Course Captur - Working on getting professor approval to record their classes and finding students able to do so - Will send out email with link to the Box page after new classes start being recorded and posted 2. Course Concerns/Donut situation - Currently, you can post a message and the ARC will be able to see it, but the ARC cannot reply to threads - We will send out a Google form until the Donut form is fully functional - You are also encouraged to pass along course concerns to any member of the ARC, and we will not share your name if you ask us not to 3. Ombuds training - A training and information session for new ombudspeople will be held on Fri-day, Oct 26th during lunch in the CTLO 4. Software Seminar - Unix Workshop this Thursday, Oct 18th, 4:15-6:15 PM in SFL - Next Sunday, we will be appointing new frosh reps! Sign-ups will be sent out and posted on the olive walk. ARC Tip of the Week The ARC website at arc.caltech.edu has more information about what the ARC does if you are interested. We meet every Sunday at 2 PM in SACB122 and our meetings are open to everyone! If you have any ques- You do not need the professor's signature tions, please feel free to email ksreedha@caltech.edu. to drop a class before add day, which is this Friday, October 19th. KITCHEN BARNEY'S GOURMET HAMBURGERS ESTABLISHED 1978 Canter's Pasaden FEED THE BRAIN mama musubi Great food choices from Barney's Gourmet Hamburgers, Canter's Deli, Mama Musubi and The Lost Cuban are just an online order away - at Pasadena's own Kitchen United. To satisfy your cognitive hunger cravings, order online or through your favorite food delivery app. To order, visit kitchenunited.com/eat kitchen united CULINARY ON DEMAND Follow us on © 2018 Kitchen United. All rights reserved 4 OCTOBER 15, 2018 ANNOUNCEMENTS THE CALIFORNIA TECH THE ACADEMICS AND RESEARCH COMMITTEE (ARC) Caltechlive! IS HOLDING INTERVIEWS FOR FRESHMAN REPRESENTATIVES NEXT SUNDAY, OCTOBER 21ST! Reduced Shakespeare Company The Complete Works of William Shakespeare (abridged) (revised) SIGN UP BY OCTOBER 19TH, 5 PM, UNDER THE RF ARCHES OR ONLINE. FOR MORE INFORMATION ON THE ARC, VISIT ARC. CALTECH.EDU.CONTACT ERIKA SALZMAN (ESALZMAN@ CALTECH.EDU) WITH QUESTIONS OR CONCERNS. THE CALIFORNIA TECH IS ACCEPTING YOUR CONTENT! JOIN THE TECH AND FIGHT FOR A BETTER MERIC DO YOU KNOW SOMETHING? WANT TO WRITE ABOUT IT? DO YOU HAVE OPINIONS? WANT TO WRITE ABOUT THEM? WE ARE ACCEPTING YOUR CONTENT, AND WILL PAY YOU IN COLD HARD It's back! All 37 plays in 97 minutes. The original and timeless classic from the Reduced Shakespeare Company. Every 10 years, The RSC goes to the source, the foun-tainhead, the birth of all things that followed CONTACT THE TECH EDITORS AT TECH@CALTECH EDU WITH YOUR ARTICLE SUBMISSION OR QUESTIONS SAT., OCT. 20, 2018 - 8 PM Caltech's Beckman Auditorium Free Parking $49, $44, $39 / $10 Youth www.events.caltech.edu - 626.395.4652 Cosponsor: AMAZON SKYMALL (Mix Case) Premium Soda Orca Choice 12 Pack $27.00文众好效公 (80 DO YOU DARET PECHKEKS MISFORTUNE COOKIES Featuring 12 unique soda flavors, Orca is here to spice up your soda life with real cane sugar. Want a particular flavor that Orca makes? Just send the seller a message with your preferences! http://a.co/d/f6JW67i Pechkeks Misfortune Cookies $32.79 This Amazon's Choice dark humor mis-fortune cookie pack is high-rated, well-priced and ready to ship immediately. "Ideal for: Lucky Lukes and Bad-luck Brians, super women and high flyers, crybabies and wussy wimps, iron ladies and tough guys! http://a.co/d/9SFmePW Miniature Violin: Small, 4 inches $19.95 女女文女次vprime Arrived at Chouse just after they closed? Professor lets class out 2 minutes late? Provide the appropriate music for the occasion with this miniature violin. http://a.co/d/oDemYs7 Enter this week's raffle for your favorite Amazon SkyMall item here: https://goo.gl/forms/fyFjk9LpRrLLKXNw2 SPORTS THE CALIFORNIA TECH OCTOBER 15, 2018 Yu Nets Twice in Comprehensive NCAA Men's Soccer Victory Winfor Women's Soccer GOCALTECH.COM Actual Sports Content Editor PASADENA (Oct. 13, 2018) - Junior Kevin Yu (Park Ridge, N.J. / Park Ridge) scored twice from set pieces for his fourth and fifth tallies of the season in a 6-1 Caltech men's soccer victory over the University of St. Katherine on a rainy Saturday afternoon. Yu's exploits vaulted him into the top five of the SCIAC points standings with 14 (five goals, four assists), just one point shy of a tie for third. Sophomore Joe Como (Glen Cove, N.Y. / Friends Acad.) made just four saves on five shots faced, but maintained a comfortable 17-save lead in the conference with 93 on the season. Caltech broke the game open early with an unrelenting high press that led to junior Robin Henry (Sprimont, Belgium / Univ. of Edinburgh) poking in a deflected cross at the back post in the eighth minute. Sophomore Rohan Mirchandani (Pleasanton, Calif. Foothill) made it 2-o in the 17th minute when he beat his defender at a dead 20-yard sprint to slot home a brilliant through ball from rookie Velissarios Christodolou (Athens, Greece / Athens Coll.). Yu then quickly wrapped the first-half scoring on a free kick from 20 yards out, sharply bending a short ball around the wall to bounce in front of and over the shoulder of the frozen USK keeper. Thesecondhalfbeganinauspiciously enough but soon threatened to be defined by significant consternation over calls from both benches, with three yellow cards and a double red eventually handed out to the visiting side while the Caltech bench was shown a yellow as well. In the midst of it all, USK broke the shutout with a ranging effort that curled inside the upper-far post, but Caltech almost immediately answered when Christodolou crashed the back post with a diving header on a perfectly placed free kick from classmate Daniel Israel (San Jose, Calif. / Lynbrook). Yu also put home a penalty kick in the 69th minute and senior Amine Boubezari (Santa Clara, Calif. / Cupertino) turned attention away from the officials with a fantastic strike that he curled in to the far post with one turn after taking the ball right off a defender's foot just outside the box. Head Coach Phil Murray and the Beavers begin their final road trip of the season at defending regular season champion University of Redlands on Wednesday, Oct. 17. 32 Junior Kevin Yu (Park Ridge, N.J. / Park Ridge) furiously dabs mid-run, just seconds after this pnotograpn was taken. -gocaltech.com SCORES October 13, 2018 Women's Soccer W 0-4 Men's Soccer W 1-6 If I make both myself and the ball levitate right above the field I can avoid friction and the referee won't notice. Phia finally paid off. GOCALTECH.COM Actual Sports Content Editor PASADENA (Oct. 13, 2018) refocused Caltech women's soccer squad put together a comprehensive shutout win over visiting Mills College, 4-0, for their second victory of the season on an overcast Saturday morning. The Beavers dominated possession to the tune of a 22-shot advantage behind marauding runs up the wing by their wide players, led bysophomore Maquelle Tiffany (Los Alamitos, Calif. / Los Alamitos), who netted her first career goal on an insurance tally in the second half. Rookie Zoe Rock (Chappaqua, N.Y. / Horace Greeley) was, more often than not, on the receiving end of those runs and long balls over the top; her ubiquitous presence all over the field translated to a season-high five shots on goal. It was junior Noelle Davis (Fort Worth, Texas / Texas Acad. of Math & Science) -gocaltech.com who staked Caltech to the lead, however, as she ran onto a through ball from sophomore Krystin Brown (Lake Forest, Calif. / Trabuco Hills) that somehow found its way through heavy traffic on the right wing. Her composed shot to the far post left the keeper with no chance for the save and gave Davis both her second tally of the year and fifth of her career. Sophomore Kali Drango (Lake Oswego, Ore. / Lake Oswego) was called upon to make just three saves in the second shutout of her career, thanks in large part to the center back pairing of classmate Nayla Abney (Sewell, N.J. / Deptford Township) and freshman Schuyler Dick (Hudson, Ohio / Walsh Jesuit), both of whom incredibly struck for late insurance goals from distance within one minute of each other. Head Coach Taylor Houck and the Beavers continue their final home stand of the season on Wednesday, Oct. 17 against the University of Redlands at 4 p.m. Shanker, Fourth Wei at Place Nationals Actual Sports Content Editor Look, ma! One hand! -gocaltech.com ROME, Ga. (Oct. 13, 2018) - Sophomores Varun Shanker (Midland, Mich. / Midland Dow) and James Wei (Chappaqua, N.Y. / Horace Greeley) wrapped up their time at the 2018 ITA Cup in Rome, Ga. with a fourth-place finish as the tournament's fourth-seeded team. The duo took on Johnson and Whaling from Gustavus Adolphus College in Saturday's third-place game. Shanker and Wei started strong, holding serve through the first five games of the opening set before Gustavus Adolphus rebounded with a late break to steal the set. Caltech held serve through the first few games of the second set as well before again succumbing to a key break from their opponents. For their efforts, the Beavers' top doubles team will enter the spring season ranked fourth in the nation among the elite doubles teams in Division Ill, the neignts or Which nave not been reached before in the history of the men's tennis program. Head Coach Jason Cohen and the Beavers will open the 2019 regular season at University of California Santa Cruz on Sunday, Feb. 10. 6 OCTOBER 15, 2018 ADVERTISEMENTS CHE CALIFORNIA TECH Bridges Got a new game here today that I wanted to see how people liked. It's called bridges or Hashiwokakero. The rules are as follows: They must begin and end at distinct islands, travelling a straight line in between. They must not cross any other bridges or islands. They may only run orthogonally (i.e. they may not run diagonally). At most two bridges connect a pair of islands. The number of bridges connected to each island must match the number on that island. The bridges must connect the islands into a single connected group. I think I'll sleep now. Puzzles from krazydad. You chose one of the most trusted institutions in SCIENCE. Now choose one of the most trusted institutions in FINANCE. CALTECH When you want unsurpassed stability, integrity and value for your money, Caltech Employees Federal Credit Union offers an honest alternative. There are no gimmicks. No annual fees. No harsh penalties. Just some of the lowest lending rates and highest savings rates in the nation... and a state-of-the-art eBranch for easy, convenient online and/or mobile access to your account. We're the overwhelming choice for financial services among the entire Caltech family. If you haven't yet joined, call or visit us online or in person today. You belong here. /CALTECH EMPLOYEES Federal Credit Union Sm arter S olutions. oven Re sults. Campus Office 515 S.Wilson Ave. (physical address) • Campus ATMs Winnett Center & Keith Spalding Building 626/395-6300 • 800/592-3328 • www.cefcu.org Must qualify for CEFCU membership to join. Minimum $5 deposit and one-time $5 membership fee due upon opening any CEFCU account. Federally insured by NCUA. PUZZLES THE CALIFORNIA TECH Mathdoku (KenKen®) How to play Mathdoku (KenKen®): Each box contains an integer from one to the number of boxes on a size. (4 for a 4x4 puzzle and 6 for a 6x6 puzzle) Every row and column must contain exactly one of each integer. The integers inside each cage (enclosed by bolded lines) must give the target number when combined with the operation shown. 4. Single box cages have no operation and just give the integer inside the cage. Puzzles from Caleb Sander. Thanks! I'd hate to die twice. It's so boring. OCTOBER 15, 2018 7 10+ 112+ 16÷ 90x 3÷ 12÷ 112x 12÷ 11- 116+ 2÷ 115+ 74 18+ 15÷ 6+ 12÷ 120x 148× 72x 12x Diagramless Crossword The diagramless crossword is similar to a standard US style crossword except in this puzzle there are five main differences: You start with an empty 17x17 grid and are required to block out the unused cells yourse 2. he clue numbers in the upper left corners are not filled in, so you have to figure out which cells are the correct ones and wri in the clue numbers in small print. The word lengths are not given, but all are at least three letters long. The completed grid will form a pattern with rotational symmetry Every white cell forms part of an Across and a Down answer Last words are for fools who haven't said enough. crossword from http://www.puzzlechoice.com Hint: 1 Across starts at Row 1, Column 5 Across 1. Actors in a play 5. Particle 9. Affirm 10. Type of star 11. Become weary 12. Matured 13. Beckon 14. Feel concern or interest 15. Female horse 16. Coiffure 21. Depend 22. Small kernels exploded by heat 23. Vegetable 24. Gustatory organ 25. Cut of meat 26. Departed 27. Lacking the necessary means or skill 31. Eggs 32. Was seated 33. Request 34. Be unwell 35. Large North American deer 37. Portion 39. Long and difficult journey 40. Speedy and brilliant 19. Physically strong rise to fame 20. Intoxicated 43. Indication 21. Review 44. First in rank or 22. Cooking utensil degree 23. Molten rock 45. Quality of voice 24. Small child 46. Boisterous 25. Angry dispute 47. At the proper time 26. Legging 48. Network of 28. Flatbottom boat horizontal and 29. Security interest vertical lines 30. Moose 51. Group of cat tle 32. Rear part of a ship 52. Uncommon 33. Part of a circle 53. Opposed to 36. Insolent 54. Graphic symbol 37. Quarry 55. Small island 38. Atmosphere 56. Portable shelter 39. Diminutive 57. Facial expression 41. Large Australian flightless bird Down 1. Narrow platform 2. Bird sanctuary 3. Tennis stroke 4. Large woody plant 5. Arboreal boa of South America 6. Garment worn in ancient Rome 7. Finished 8. Constructed 15. Compliant 16. Flexible pipe 17. Pertinent 18. Frozen water 42. Lubricant 43. Enlisted person 45. Hard-shelled reptile 47. Thick 48. Fortitude and determination 49. Speed competition 50. Golf club 51. Precipitation of ice pellets HUMOR 8 OCTOBER 15, 2018 THE CALIFORNIA TECH Silent Observations R. Carson Have you ever really looked at your fingernail? Of course there's this but fingernails clearly don't? And what about the little blue spots that little weird bit on the edge that isn't sure if it wants to be skin or nail, which sometimes show up after I finish an exam- is the ink seeping through my is a pretty pathetic show of spinelessness if you ask me, and there's the finger and depositing itself in the underside of the nail? If fingernails weird white lines that sometimes show up when you slam your finger in a are secretly sucking the ink out of my body I am going to be VERY upset. door to mock you for your lack of coordination and/or situational awareness, I would get rid of them if I could, but the freaky little parasites have and those things are terrible, but that's all pretty obvious. I mean REALLY securely grafted themselves to me, like one of those deep sea isopods really looked. There's some pretty weird shit going on there. Like how if you that eats and replaces tongues. Maybe that's what fingernails are- hold a nail up to the light just right, you can sometimes see these thin vertical they've got the segmented bands, as previously mentioned, and it would breaks in the reflection that run along your finger axis. What are those? explain the deeply seated, pre-linguistic revulsion. It's hard to say. But Are my fingernails woven together from thin flat strips of keratin, like some just to be safe, I think it would be best that all infants have a DDT incredibly low quality globe? Why would you even do that when the whole coating applied at birth, to kill off any arthropods that might try to point of making globes that way is that spheres have intrinsic curvature replace their precious fingertips. You can never be too careful. Answers to Puzzles and Crossword: http://bit.ly/2PGXIty Haha, they look like they're Oh wait. having fun playing together! Did you know that these Oh no. Now that The California Tech little quus are other one is... Editors-in-Chief capable of coying...? Sophie Piao Amrita Rhoads team- Is that Milan Roberson Daniel Xu one aoin Hmm. ٨-١٠ bathroom? Page Editors Reggy Granovskiy Circulation Manager Daniel Xu Oh, now he's laughing адаіл! Cute!) Come on, quus! They deserve some privacy, too! Maube SO. Food $200 Vataなりて Rent $800 The Tech $360 Utility $150 HmmMmm. Frosh, this Problem isn't even that hard Sophie Piao (b. 1997) techers at the zoo (someone who is good at the economy please help me budget this. my frosh are dying), 2018 Advisor Richard Kipling Caltech 40-58, Pasadena, CA 91125 contact tech@caltech.edu The Tech is published weekly except during vacation and examination veriods bv the Associated student of the California Institute of Technology, Inc. The opinions expressed herein are strictly those of the authors and advertisers. etters and submissions are we come: e-mail submis sions to tech@caltech.edu as plain-text attachments including the author's name, by Friday of the wee berore pubncaton. Ine leen aoes accept anonymou contributions under special circumstances. The edi tors reserve the right to edit and abridge all submis sions for any reason. All written work remains prop erty or its author 'The adverusing deadline is 5 v.m. Fridav: all advertis ing should be submitted electronically or as camera-ready art, but The Tech can also do simple typesetting and arrangement. All aaverusing moules shoula D directed to the business manager at tech@caltech.edu We are always accepting submissions for comics, and will pay you. Letters from the Editors-in-Chief Amrita Rhoads: if you dm me a song rec i promise to listen to it at least once Sophie Piao: dm me if u wanna see a spicier version of the comic :^) also ascit it's joke!!! B lease dont cut our funding we r a valuable community resource Milan Roberson: I hope this gives me all of the powerups available for Tech editors... The California Tech Caltech 40-58 Pasadena, CA 91125 Dan Xu: Thank you for helping with the Caltech Cohort Study. Your choices have earned you $39.25. This week's recommended Tech usage after reading is: reminding yourself when and where you can register to vote (Monday-Wednesday outside Chandler during lunch). 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